首页> 外国专利> Monoclonal antibody specific to human neutrophil(s) - produced by new hybridoma cell line ATCC-HB-9445 derived from mouse spleen cells immunised with purified human granulocytes

Monoclonal antibody specific to human neutrophil(s) - produced by new hybridoma cell line ATCC-HB-9445 derived from mouse spleen cells immunised with purified human granulocytes

机译:对人嗜中性粒细胞具有特异性的单克隆抗体-由杂交瘤细胞新ATCC-HB-9445产生,衍生自用纯化人粒细胞免疫的小鼠脾细胞

摘要

A cell line is claimed, produced by a hybridoma technique, which produces a monoclonal antibody which binds specifically to the ID3 antigen of neutrophils. Monoclonal antibody is also claimed, which binds specifically to the ID3 antigen and is further characterised as not binding to human acute leukemia cells and other human peripheral blood cells and not binding significantly to granulocyte precursors in bone marrow.
机译:要求保护的细胞系是通过杂交瘤技术产生的,该细胞系产生特异性结合嗜中性粒细胞的ID3抗原的单克隆抗体。还要求保护的是与ID3抗原特异性结合的单克隆抗体,其进一步特征在于不与人急性白血病细胞和其他人外周血细胞结合,并且不与骨髓中的粒细胞前体显着结合。

著录项

  • 公开/公告号ES2008956A6

    专利类型

  • 公开/公告日1989-08-16

    原文格式PDF

  • 申请/专利权人 COULTER CORPORATION;

    申请/专利号ES19880000066

  • 发明设计人 GRIFFIN JAMES D.;

    申请日1988-01-12

  • 分类号C12N15/00;C12N5/00;G01N33/577;

  • 国家 ES

  • 入库时间 2022-08-22 06:36:38

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