CLONING AND EXPRESSION VECTORS OF .GAMMA. INTERFERON, TRANSFORMED BACTERIAS AND PREPARATION PROCESS OF .GAMMA. INTERFERON

摘要

PATENT "Cloning Vectors and expression of interferon-.gamma., Transformed bacteria and method for preparing the interferon-.gamma.". Transgene SA Invention: Paul Sondermeyer Michael COURTNEY Luc-Henri TESSIER Jean Pierre LECOCQ SHORT DESCRIPTION The present invention relates to an expression vector of the mature protein of interferon-.gamma. in bacteria of the type comprising the gene coding for the mature protein of interferon-.gamma. human and plasmid elements ensuring the expression of this gene characterized in that the 5 'end of the sequence encoding the mature protein is as follows: Bacteria transformed by these vectors can produce IFN-.gamma. with high yields.