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PHARMACEUTICAL PREPARATIONS CONTAINING FLAVENE OR THIOFLAVENE DERIVATIVES, THE USE THEREOF, NOVEL FLAVENES AND THIOFLAVENES, AND PROCESSES FOR THEIR MANUFACTURE
PHARMACEUTICAL PREPARATIONS CONTAINING FLAVENE OR THIOFLAVENE DERIVATIVES, THE USE THEREOF, NOVEL FLAVENES AND THIOFLAVENES, AND PROCESSES FOR THEIR MANUFACTURE
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机译:包含黄酮或硫代黄酮衍生物,其用途,新型黄酮和硫代黄酮及其制造过程的药物制剂
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摘要
Pharmaceutical preparations containing flavene or thioflavene derivatives, the use thereof, novel flavenes and thioflavenes, and processes for their manufacture. The invention relates to pharmaceutical preparations containing compounds of formula I IMG (I), in which X1 and X2, independently of each other, represent hydrogen, halogen, unsubstituted or substituted amino or a quaternary ammonium sa etherified or esterified hydroxy; free, etherified, esterified or oxidized mercapto; nitro; functionally modified formyl; free or functionally modified carboxyl; acyl; an unsubstituted or substituted hydrocarbon radical, or an unsubstituted or substituted heterocyclic radical; with the proviso that at least one of the radicals X1 and X2 is bonded by a carbon atom to the ring system and with the proviso that X1 and X2 cannot be together halogen and formyl; in which Y represents oxygen, sulfur, sulfinyl or sulfonyl but must be sulfur, sulfinyl or sulfonyl, if X1 is hydrogen and X2 is formyl; and the rings A and B are each unsubstituted or substituted; or pharmaceutically acceptable salts of such compounds that contain a salt-forming group, and to novel compounds of formula I. The compounds are useful e.g. for the treatment of diseases of the respiratory tract and of liver diseases. The are prepared by methods known per se.
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