首页> 外国专利> A positive retroregulatory element, plasmid and cells comprising said element and their production, a method of enhancing gene expression using said element and a method of enhancing RNA half life using said element

A positive retroregulatory element, plasmid and cells comprising said element and their production, a method of enhancing gene expression using said element and a method of enhancing RNA half life using said element

机译:阳性逆调控元件,包含所述元件的质粒和细胞及其产生,使用所述元件增强基因表达的方法和使用所述元件增强RNA半衰期的方法

摘要

The invention concerns a method for extending the half-life of RNA's. The half-life extension is conferred upon the RNA by a co-transcribed positive retroregulatory element which is ligated to the 3 min end of the DNA sequence coding the RNA. RNAs having an extended half-life conferred by a co-transcribed positive retroregulatory element are also claimed.
机译:本发明涉及延长RNA的半衰期的方法。半衰期延长是通过共转录的正逆向调控元件赋予RNA的,该元件与编码RNA的DNA序列的3分钟末端连接。还要求保护具有由共转录的正逆转录调控元件赋予的延长的半衰期的RNA。

著录项

  • 公开/公告号EP0174785B1

    专利类型

  • 公开/公告日1989-07-19

    原文格式PDF

  • 申请/专利权人 CETUS CORPORATION;

    申请/专利号EP19850306183

  • 申请日1985-08-30

  • 分类号C12N15/00;C12P21/00;C12N5/00;C12P19/34;

  • 国家 EP

  • 入库时间 2022-08-22 06:35:03

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