Piperidine derivatives in the treatment of extrapyramidal side effects associated with neuroleptic therapy

摘要

The present invention pertains to the use of a class of serotonin 5HT₂ antagonists of the formula: wherein:each of R¹, R², R³, and R⁴ are independently selected from the group consisting of hydrogen, a C₁₋₆ alkyl group, halogen, trifluoromethyl, hydroxy, a C₁₋₆ alkoxy group, or an amino group; n is 2, 3, or 4; and the pharmaceutically acceptable acid addition salts thereof for the preparation of a pharmaceutical composition for the treatment of the extrapyramidal side effects associated with neuroleptic drug therapy.