AQUEOUS SOLUTION OF SILK FIBROIN HAVING EXCELLENT STORAGE STABILITY AND PRODUCTION THEREOF

摘要

PURPOSE:To provide an aqueous solution of silk fibroin containing specific amounts of a polyol, a fungicidal and antiseptic agent and a chelating agent, having characteristics such as moderate moisture-absorption and humectant property, stably storable over a long period and useful as a cosmetic base and a food base. CONSTITUTION:The objective homogeneous aqueous solution of silk fibroin containing 0.1-5% of a polyol selected from a =2-hydric alcohol, its polymer and a polyvinyl alcohol, 0.02-1% of a fungicidal and antiseptic agent and 0.02-1% of a chelating agent can be produced by mixing (A) an aqueous solution of silk fibroin produced by dissolving the fibroin in an aqueous medium and (B) 0.02-1% of a chelating agent (e.g., EDTA or sodium tripolyphosphate) in terms of the solution concentration and then with (C) a 0.2-20% solution of a fungicidal and antiseptic agent (e.g., benzoic acid) produced beforehand by using a polyol (e.g., ethylene glycol) as a solvent.