首页> 外国专利> Process for modifying the metabolism of host cells recepotoras, vector of transfeccao and / or transformation of cells.Processes for the treatment of a condition of malfunction in a cell and to treat or prevent the malfunction of cells selected

Process for modifying the metabolism of host cells recepotoras, vector of transfeccao and / or transformation of cells.Processes for the treatment of a condition of malfunction in a cell and to treat or prevent the malfunction of cells selected

机译:改变宿主细胞白细胞的代谢,转染载体和/或细胞转化的方法。用于治疗细胞功能失常的病症以及治疗或预防所选细胞功能失常的方法

摘要

A piece of useful nucleic acid is linked to a cell homing factor, for instance a cell receptor such as that for the epidermal growth factor (EGF), and the resulting coupled system is used to transfect and/or transform suitably selected host cells. This technique provides internalization in high yields and constitutes a significant advance over classic transfection, e.g. with CA++ ions.
机译:一条有用的核酸连接至细胞归巢因子,例如细胞受体,例如表皮生长因子(EGF)的受体,并且所得的偶联系统用于转染和/或转化合适选择的宿主细胞。该技术提供了高产量的内在化作用,并构成了比经典转染例如与CA + + +离子。

著录项

  • 公开/公告号BR8707617A

    专利类型

  • 公开/公告日1990-05-15

    原文格式PDF

  • 申请/专利权人 BATTELLE MEMORIAL INSTITUTE;

    申请/专利号BR19878707617

  • 发明设计人 ANDREW E. MYERS;

    申请日1987-12-29

  • 分类号C12N15/00;

  • 国家 BR

  • 入库时间 2022-08-22 06:19:57

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