PROCEDURE FOR PROGRESSING SOLUTION OF SOLVENTLY LYOFILIZED MEDICINAL PRODUCTS AND CONTINUING THE IMPLEMENTATION OF THE PROCEDURE.

摘要

In a method of accelerating the dissolution of hard-soluble lyophilized medicaments based on proteins, a magnetic body 13 is introduced into an end container 6 under sterile conditions prior to the lyophilization of the batch. The end container 6 is brought into the region of a magnetic rotary field after addition of a solvent to the lyophilized batch, whereupon the magnetic body 13 is set in motion. An arrangement for carrying out the method includes a heatable block 2 of antimagnetic material with one or more accommodation openings 3, 3', 3'' etc. for the end containers. A rotating magnetic stirrer 8 is installed below the accommodation openings. IMAGE