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ANALOGIFREMGANGSMAADE FOR THE MANUFACTURE OF acid addition salts of 3alfa-acyloxy-2beta, 16beta-dipiperidino-5alfa-androstane derivatives, AND METHOD FOR THE MANUFACTURE OF PHARMACEUTICAL solutions thereof
ANALOGIFREMGANGSMAADE FOR THE MANUFACTURE OF acid addition salts of 3alfa-acyloxy-2beta, 16beta-dipiperidino-5alfa-androstane derivatives, AND METHOD FOR THE MANUFACTURE OF PHARMACEUTICAL solutions thereof
New and pharmacologically useful pharmaceutically acceptable acid addition salts are disclosed for the 16 beta -mono-quaternary ammonium derivatives of either the 2 beta , 16 beta -bis-piperdino-3- alpha , 17 beta -dihydroxy-5 alpha -androstane 3 alpha , 17 beta -di-lower aliphatic esters of the 2 beta , 16 beta -bis-piperidino-3 alpha -hydroxy-5 alpha -androstane-3 alpha -lower aliphatic esters, which salts are surprisingly relatively stable in aqueous solutions, so that they provide stable aqueous injection preparations.
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