A method for in vivo production of astaxanthin Phaffia rhodozyma yeast with increased astaxanthin content

摘要

An economical process for the in vitro production of carotenoids, particularly the pigment astaxanthin, and particularly a process for enhancing astaxanthin content of cultures of microorganisms of genus Phaffia, the process comprising culturing a microorganism of genus Phaffia in a nutrient medium containing an antibiotic, cytochrome B inhibitor, or a terpenoid synthetic pathway inhibitor, or subjecting said microorganism to growth in the presence of a metabolic pathway inhibitor, particularly a main respiratory pathway inhibitor, in the presence of an influence which triggers a secondary respiratory pathway.