Process for the preparation of therapeutically active 1,4,5,7-tetrahydro furo / 3,4-b / pyridine derivatives

摘要

Dihydropyridines of the formula IMAGE in which R1, R2, R5 and R6 can be hydrogen or various halogen or organic radicals, R4 is an optionally substituted hydrocarbon radical, A is a direct bond, a C1-C20-alkylene chain or a C2-C20-alkenylene chain, which chains are optionally interrupted by O or S X is O or S, and Y is a direct bond, O, S, -NH-or-N-alkyl with 1 to 8 C atoms or a pharmaceutically acceptable salt, are useful as cardiotonic agents for improving heart contractility, antihypotonic agents, for lowering the blood sugar level, for detumescing mucous membranes and for influencing the salt and/or liquid balance.