PROCESS FOR PRODUCING NEW 1',2'-DIHYDROSPIRO SQUARE BRACKETS OPEN IMIDAZOLIDINE-4,4'(3'H)-QUINOLINE SQUARE BRACKETS CLOSED DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THESE COMPOUNDS AS ACTIVE INGREDIENT

摘要

Spiro-imidazolidines of the formula: …CHEM… and the pharmaceutically acceptable salts thereof, wherein X is O, CH2 or NH; R is hydrogen, fluoro, chloro, methyl or methoxy; and Y is O or CH2. …??These compounds are useful in treatment to prevent or alleviate ocular or neuritic diabetes-associated chronic complications.