首页>
外国专利>
(1H-AZOL-1-YLMETHYL)SUBSTITUTED QUINOLINE,QUINAZOLINE OR QUINOXALINE DERIVATIVES,THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
(1H-AZOL-1-YLMETHYL)SUBSTITUTED QUINOLINE,QUINAZOLINE OR QUINOXALINE DERIVATIVES,THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
展开▼
机译:(1H-氮杂-1-基)取代的喹啉,喹喔啉或喹喔啉衍生物,其制备和组成它们的药物成分
展开▼
页面导航
摘要
著录项
相似文献
摘要
Novel (1H-azol-1-ylmethyl)substituted quinoline, quinazoline or quinoxaline derivatives of formula CHEM the pharmaceutical acceptable acid addition salts thereof and the stereochemically isomeric forms thereof, wherein -X1=X2- is -CH=CH-, -CH=N-, or -N=CH-; R is hydrogen or C1-6alkyl; Y is hydrogen, C1-10alkyl, C3-7cycloalkyl, Ar1, Ar2-C1-6alkyl, C2-6alkenyl or C2-6alkynyl; Z is a radical of formula CHEM CHEM which compounds are useful for treating disorders which are characterized by an excessive proliferation and/or abnormal differentiation of epithelial tissues: pharmaceutical compositions containing such compounds as an active ingredient and methods of preparing said compounds and pharmaceutical compositions.
展开▼