PROCESS FOR THE PRODUCTION OF THE ANTIBIOTIC COMPLEX A10255 AND ITS FACTORS

摘要

Newly-discovered antibiotic A10255 factors B, C, E, F, G and H are produced by submerged aerobic fermentation of Streptomyces gardneri NRRL 15537, NRRL 18260, NRRL 15922, or an A10255-producing variant or mutant thereof. The antibiotics are active against a wide variety of pathogenic bacteria, and also enhance feed-utilization efficiency in domestic animals. The antibiotics can also be used to detect the thiostrepton-resistance gene in Streptomyces species.