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therapeutic compositions for controlled release of drugs supportatisu polymer grids and coated with polymer films and their preparation process
therapeutic compositions for controlled release of drugs supportatisu polymer grids and coated with polymer films and their preparation process
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机译:用于控制释放支持药物的聚合物网格并涂有聚合物薄膜的药物的治疗组合物及其制备方法
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摘要
The described therapeutic compositions with controlled release of medicaments comprise a medicament loaded onto particles of a crosslinked non-ionic polymer insoluble but swellable in water, using either swelling with solutions of the medicament or high-energy co-grinding methods. The medicament-loaded particles are coated with a polymers film able to control medicament release, to obtain a prolonged release of the medicament (even exceeding 24 hours) while maintaining high bioavailability.
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