PURIFIED ANTIGEN FROM NON-A, NON-B HEPATITIS CAUSING FACTOR

摘要

Purified Antigen From Non-A,Non-B Hepatitis Causing FactorAbstractAn isolated, purified non-A, non-B hepatitis(NANBH) associated antigen having the properties (a)molecular weight of monomer 77,000 daltons on sodiumdodecyl sulphate polyacrylamide gel, (b) monomerreactive with rhesus monkey immune serum, (c)glycoprotein containing about 2% carbohydratecomprising (i) predominantly mannose and (ii)approximately equal molar amounts of fucose andgalactose, (d) an aromatic amino acid compositioncomprising molar ratios of phenylalanine, tyrosine, andtrypotophan of about 3:3:1, respectively, and (e)immunogenicity is disclosed along with methods ofpreparing and using the antigen.