PROCESS FOR PURIFICATION OF ISLET CELLS; MONOCLONAL ANTIBODIES DIRECTED TO ISLET AND ACINAR CELLS; AND PROCESS FOR MAKING AND USING SAME

摘要

The present application relates to the identification and purification of islet cells which are the cells responsible for the production of insulin in mammals, and preferably, human islet cells, using monoclonal antibodies specifically directed to these cells. Further, this application is directed to the monoclonal antibodies useful in the isolation and purification of islet cells. This application is also directed to a method of making the subject monoclonal antibodies and use of the same in the detection of cells for diagnostic purposes.