RECOMBINANT EXPRESSION SYSTEM BASED ON SATELLITE TOBACCO MOSAIC VIRUS

摘要

The present invention provides the sequence of the RNA genome of satellite tobacco mosaic virus. Based on said sequence and the discovery that heterologous RNA can be accommodated in said genome without eliminating replicability, the invention provides compositions comprising modified genomes of the virus, or cDNAs of such genomes, to transform plant cells in vitro and in vivo to make desired RNAs or proteins. Further, the invention provides methods and intermediates for making such compositions and methods of using such compositions.