Recombinant DNA expression vectors and DNA compounds that encode isopenicillin N synthetase from streptomyces lipmanii

摘要

DNA compounds encoding an isopenicillin N synthetase (IPNS) gene are useful for constructing a variety of recombinant DNA vectors. The vectors are useful in producing IPNS in a wide variety of host cells, such as Streptomyces, Penicillium, and Cephalosporium. DNA compounds encoding the tran­scription and translation activating sequence and transcription termination sequence of the IPNS gene are also useful in the construction of expression vectors.