CYSTEINE-DEPLETED MUTEINS OF BIOLOGICALLY ACTIVE HUMAN TUMOR NECROSIS FACTOR PROTEINS

摘要

human tumor necrotic factor mutu00e9ines synthetic biologically active (htnf) where at least one of the two cysteine residues were deleted or replaced by another amino acid to eliminate the intermolecular cross-linking sites.the invention also relates to a structural gene with a synthetic dna sequences specifically designed for the coding of synthetic htnf mutu00e9ines is described.