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SEQUENTIAL IMPROVED METHOD FOR TREATMENT OF HUMAN BLOOD-CLOTTING FACTOR PRODUCTS.
SEQUENTIAL IMPROVED METHOD FOR TREATMENT OF HUMAN BLOOD-CLOTTING FACTOR PRODUCTS.
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机译:序贯改进的人血凝集因子产品的治疗方法。
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摘要
a concentrate of factor viii and factor ix concentrate, or a concentrated fibrinogen and other coagulation factor product is subjected to a sequence of steps of heating to reduce the infectivity of a virus (such as hepatitis or serve they cause aids), as the case may be.the heating is carried out while the concentrate is lyophilized or dried by another process. the steps of heating the sequence is carried out in at least two different lengths, and at least two different temperatures. after the heating sequence, the concentrate is reconstituted for use.the sequential process is to obtain a greater inactivation of different viral forms, or a reduction in the heating process is required, or both. this reduction in the heating process is required to manifest itself in the form of a generally reduced heating time, or a total energy consumption is reduced, or both.one of the advantages of the invention include an enhanced level of quality assurance. also, the invention provides opportunities for the preparation of vaccines against the virus, if a sufficient amount of the virus present in the concentrate.
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