首页> 外国专利> 1.4 - dihydro - 5 - isopropoxy - 2 - methyl - 4 - (2 - trifluormethylphenyl) - 1.6 - naphthyridin - 3 - carboxylic acid - 2 - (n - methyl - n - phenylmethylamino) - ethyl ester fumarate in optically isomeric forms, procedures to manufacture and product

1.4 - dihydro - 5 - isopropoxy - 2 - methyl - 4 - (2 - trifluormethylphenyl) - 1.6 - naphthyridin - 3 - carboxylic acid - 2 - (n - methyl - n - phenylmethylamino) - ethyl ester fumarate in optically isomeric forms, procedures to manufacture and product

机译:1.4-光学异构形式的富马酸酯富马酸酯-二氢-5-异丙氧基-2-甲基-4-(2-三氟甲基苯基)-1.6-萘啶-3-羧酸-[2--(n-甲基-n-苯基甲基氨基)-乙基]富马酸酯,生产程序和产品

摘要

The invention relates to (+/-)-1,4-dihydro-5-isopropoxy-2-methyl- 4-(2-trifluoromethylphenyl)-1,6-naphthyridine-3-carboxylic acid 2-(N-methyl-N-phenylmethylamino)ethyl ester fumarate and the optical isomers (+)-1,4-dihydro-5-isopropoxy-2-methyl- 4-(2-trifluoromethylphenyl)-1,6-naphthyridine-3-carboxylic acid 2-(N-methyl-N-phenylmethylamino)ethyl ester fumarate and (-)-1,4-dihydro-5-isopropoxy-2-methyl-4-(2-trifluoromethylphenyl)- 1,6-naphthyridine-3-carboxylic acid 2-(N-methyl-N-phenylmethyl- amino)ethyl ester fumarate, their preparation and use in medicaments for controlling high blood pressure and cardiac and vascular disorders.
机译:本发明涉及(+/-)-1,4-二氢-5-异丙氧基-2-甲基-4-(2-三氟甲基苯基)-1,6-萘啶-3-羧酸2-(N-甲基-N富马酸-苯基甲基氨基)乙酯和光学异构体(+)-1,4-二氢-5-异丙氧基-2-甲基-4-(2-三氟甲基苯基)-1,6-萘啶-3-羧酸2-(N -富马酸酯-甲基-N-苯基甲基氨基)乙酯和(-)-1,4-二氢-5-异丙氧基-2-甲基-4-(2-三氟甲基苯基)-1,6-萘啶-3-羧酸2-(富马酸N-甲基-N-苯基甲基-氨基)乙酯,它们的制备和用于控制高血压以及心脏和血管疾病的药物。

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