Use of 2 - tert - alkyl imino - 2 - di - c (arrow down) 1 (arrow down) (arrow down) - (arrow down) (arrow down) 4 (arrow down) - alkylamino - 1,3 - di - c (arrow down) 1 (arrow down) (arrow down) - (arrow down) (arrow down) 3 (arrow down) - alkyl - - - perhydro 1,3,2 diazaphosphorine for 0 - substitution reactions of ribo identical of nucleotides

摘要

2-tert.-alkylimino-2-di-C1-4-alkylamino-1,3-di-C1-3-alkylperhydro-1,3, 2-diazaphosphorines are suitable for O-substitution of protected ribonucleosides with alkyl, alkenyl or aralalkyl groups in the presence of corresponding group-transfer compounds.