首页> 外国专利> A method for the preparation of microcapsules, which a fast release of active substance from them, which can be produced from them and / or to the tablets and the direct tableting of active ingredients for medicaments guaranteed or strips

A method for the preparation of microcapsules, which a fast release of active substance from them, which can be produced from them and / or to the tablets and the direct tableting of active ingredients for medicaments guaranteed or strips

机译:一种制备微胶囊的方法,该方法可从其中快速释放活性物质,该活性物质可从它们和/或片剂中生产出来,并直接压片有保证的药物或带状药物的活性成分

摘要

the subject of the invention is a method for the production of mikrokapseln the rapid delivery of the active agent from them or from them herstellbaren tablets and the direct tablettierung of arzneimittelwirkstoffen ensureby mikroverkapseln of 1 or more in cyclohexane insoluble substance (s) with kristallteilchengru00f6u00dfen exceeding 1000 m in cyclohexane with u00e4thylcellulose in gewichtsverhu00e4ltnissen of 1: 30 to 1: 5, relative to the weight of the nuclear material in which $a (a) the mikroverkapseln in cycl ohexan with u00e4thylcellulose in the presence of 0.001 to 1.0% (w / w / vol.-% of one or more soluble anionic surfactant cyclohexane compound (s) related to the cyclohexane is undertaken and / or $a (b) after the mikroverkapseln with u00e4thylcellulose treatment with u00e4thylcellulose mikroverkapselten wirkstoffteilchen with 0.001 to 1.0% w / w / vol.-% solution of 1 or more anionic surface active substance (s) in cyclohexane is carried out.
机译:发明内容本发明的主题是一种用于生产米卡普西林的活性剂的方法,所述方法包括从米曲卡普林片中快速递送活性剂,或从其中快速递送活性成分,并通过米卡维普西卡普尔中的一种或多种环己烷不溶性物质中的kristallteilchengr u00f6来直接递送arzneimittelwirkstoffen的直接片剂。在环己烷中,在基威奇韦尔中的乙基纤维素的比重超过1000 m,比例为1:30至1:5,相对于其中$ a(a)在环己烯中的环己酮与 u00e4纤维素存在下的核材料的重量0.001至1.0%(w / w / vol .-%的一种或多种与环己烷有关的可溶性阴离子表面活性剂环己烷化合物)和/或$ a(b)用三甲基纤维素处理并用用在环己烷中的一种或多种阴离子表面活性物质的0.001至1.0%w / w / vol .-%的溶液来进行纤维素基纤维素的制备。

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