Conjugates of the hydrazide of vinca alkaloid binds to an immunoglobulin, and pharmaceutical compositions comprising

摘要

Active conjugates incorporating a substance with anticancer activity and a steering agent of the immunoglobulin type, the substance with anticancer activity and the steering agent being linked by a covalent bond of the hydrazide type. They consist of hydrazide derivatives of vinca alkaloid bonded to an immunoglobulin. Process for the preparation of these active conjugates and pharmaceutical compositions containing them.