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ANTIPHLOGISTIC AND ANALGESIC PATCH

机译:止痛和止痛贴

摘要

PURPOSE:To obtain an antiphlogistic and analgesic patch having excellent durability of medicinal effects and low irritation to the skin, comprising 4- biphenylyl acetic acid as an active ingredient and crotamiton as an absorption auxiliary. CONSTITUTION:A base component obtained by neutralizing a polyacrylic acid and/or a polyacrylic acid copolymer with a water soluble organic amine into pH6-8 is blended with 0.1-5wt.% 4-biphenylyl acetic acid and 0.01-5wt.% crotamiton. The blend is properly mixed with a conventional humectant, a thickening agent, a preservative, etc., as other components, prepared and spread to a sheetlike substrate such as cloth or paper to give the objective substance. The polyacrylic acid and/or polyacrylic acid copolymer is used as a thickening a gent, can stably dissolve 4-biphenylyl acetic acid and will not precipitate as crystal.
机译:用途:获得一种具有优异的药效持久性和对皮肤低刺激性的消炎镇痛贴剂,该贴剂包含4-联苯乙酸作为活性成分,以及克罗米通作为吸收助剂。组成:将聚丙烯酸酯和/或聚丙烯酸酯共聚物与水溶性有机胺中和至pH6-8所获得的基础组分与0.1-5wt。%的4-联苯基乙酸和0.01-5wt。%的巴豆酰胺混合。将该混合物与常规的保湿剂,增稠剂,防腐剂等作为其他组分适当地混合,制备并铺展到片状基材如布或纸上以得到目标物质。聚丙烯酸和/或聚丙烯酸共聚物用作增稠剂,可以稳定地溶解4-联苯基乙酸,并且不会以晶体沉淀。

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