THERAPEUTIC COMPOSITION FOR TREATING LEUKEMIA CHARACTERIZED BY POLYPEPTIDE CONTAINED THEREIN AND HAVING ACTIVITY OF HUMAN INTERLEUKIN 2

摘要

PURPOSE: To obtain a medical composition for treatment of leukemia, especially acute myeloblastic leukemia by including a polypeptide having human interleukin 2 (IL-2) activities. CONSTITUTION: This medical composition includes natural human IL-2, recombinant human IL-2, or allelomorph or derivative thereof, preferably recombinant IL-2, especially reduced type and not glycosylated recombinant IL-2. The composition is administered by an intravenous route by slow bolus, continuous perfusion, muscle route or subcutaneous administration. The divided parenteral dose of the IL-2 is within the range of 2-20106 U/M2 and the administration is performed by repeated administration of 2 times per day in a cycle of several days per week, or by repeated administration for at least unsuccessive 3 weeks.