METHOD OF ANALOGY FOR THE PREPARATION OF HYDROXYDE DERIVATIVES OF 1- (P-METHOXYBENZOYL) -2-PYRROLIDONE AND PROTECTED HYDROXYDER DERIVATIVES OF 1- (P-METHOXYBENZOYLENE VENEDLEDENE-PYRROLIDONE-2-PYRROLIDONE-PYRROLIDONE-2-PYRROLEDONE

摘要

1-Substituted-2-pyrrolidinones of the formula IMAGE I wherein one of R1, R2 and R3 represents hydroxy and the remaining substituents represent hydrogen, are capable of counteracting cerebral insufficiency produced experimentally in animal tests. They can be used therapeutically in the control or prevention of cerebral insufficiency or in the improvement of intellectual capacity. They can be manufactured from novel intermediates and can be processed to provide medicaments.