PROCESS FOR PRODUCING MEVALONIC ACID DERIVATIVES CONTINING PYRAZOLO-PYRIDINE RING AND PHARMACEUTICAL COMPOSITIONS CONTINING THEM AS ACTIVE COMPONENTS

摘要

The present invention relates to compounds of the formula: CHEM where Y is -CH2-, -CH2CH2-, -CH=CH-, -CH2-CH=CH-, -CH=CH-CH2-, -C(CH3)=CH- or -CH=C(CH3); Z is -Q-CH2WCH2-CO2R12, CHEM (wherein Q is -C(O)-, -C(OR13)2- or -CH(OH)-; W is -C(O)-, -C(OR13)2- or -C(R11)(OH)-; and their pharmaceutical uses as anti-hyperlipidemic, hypolipoproteinemic and anti-atherosclerotic agents.