首页> 外国专利> PROCESS FOR PRODUCING NEW 6-METHYL-19-NOR-STEROIDS, PHARMACEUTICAL PREPARATIVES CONTAINING THEM AND TRANSFORMATION THEM INTO 19-NOR-PREGNA-DIENES SUBSTITUTED IN 17-ALPHA POSITION

PROCESS FOR PRODUCING NEW 6-METHYL-19-NOR-STEROIDS, PHARMACEUTICAL PREPARATIVES CONTAINING THEM AND TRANSFORMATION THEM INTO 19-NOR-PREGNA-DIENES SUBSTITUTED IN 17-ALPHA POSITION

机译:制备新的6-甲基-19-异甾烷酸酯,包含它们的药物制剂并将其转化为取代的17-异戊二烯的17-α-二聚体的方法

摘要

The invention relates to the field of organic chemistry and to steroid chemistry in particular. Its particular subject are novel 6-methyl estra 4,6-dienes of general formula (I) in which A is hydrogen or a lower oxoalkyl radical and B is hydrogen, or A is a free or esterified hydroxyl and B is a lower alkyl radical or a lower alcynyl radical, or A and B together form the oxygen of a cetone. The invention also relates to a method of obtaining compounds of general formula (I). These compounds are valuable synthesis agents which make it possible to obtain pharmacologically active 6-methyl 19-nor pregna 4,6-dienes.
机译:本发明涉及有机化学领域,尤其涉及类固醇化学。其具体主题是通式(I)的新型6-甲基雌二醇4,6-二烯,其中A为氢或低级氧代烷基,B为氢,或A为游离或酯化的羟基,B为低级烷基。或低级炔基,或A和B一起形成丙酮的氧。本发明还涉及获得通式(I)的化合物的方法。这些化合物是有价值的合成剂,其使得可能获得具有药理活性的6-甲基19-去甲孕烷4,6-二烯。

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