method for preparing 1,3 - di substituted nitrosoureumderivaten; methods for the preparation of a pharmaceutical preparation that contains such a nitrosoureumderivaat antitumour activity.and the formed pharmaceutical preparation.

摘要

The invention relates to the preparation of novel N-substituted alkyl-N-nitrosocarbamoyl azides and to the compounds obtained thereby. The novel N-substituted alkyl-N-nitrosocarbamoyl azides can be reacted with amines, diamines, aminoalcohols, aminoacids or aminoacid derivatives to prepare unsymmetrically 1,3-disubstituted nitrosoureas which show therapeutical activity.