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Novel conjugates associating, by a covalent bond, an enzyme, and an antibody, and combinations drug using said conjugates
Novel conjugates associating, by a covalent bond, an enzyme, and an antibody, and combinations drug using said conjugates
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机译:通过共价键将酶和抗体结合的新型结合物,以及使用所述结合物的组合药物
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摘要
The present invention relates to new immunoenzymic conjugates resulting from a chemical coupling, by covalent bond, of an antibody or a fragment of antibody, which has retained the capacity of recognizing the selected antigen, with an enzyme capable of producing ammonium ions from natural substrates which are well tolerated in higher animal organisms. The invention also relates to a process for the preparation of these conjugates and the medicinal associations of said conjugates with an immunotoxin.
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