METHOD FOR THE PREPARATION OF 4-HYDROXY-TETRAHYDROPYRANE-2-ONES AND THEIR DERIVATIVES OF DIHYDROXY-CARBOXYLIC ACIDS, SALTS AND ESTERS, AND OF PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND INTERMEDIATE COMPOUNDS

摘要

Compounds of the formula I …IMAGE… and the corresponding open-chain dihydroxy carboxylic acids of the formula II …IMAGE… in which X, Y, R1, R2, R3, R4, R5 have the stated meanings, and their pharmacologically acceptable salts with bases and their pharmacologically acceptable esters, process for the preparation of these compounds, their use as drugs, and pharmaceutical preparations are described. Also described are compounds of the formula III …IMAGE… in which R1, R2, R3, R4, R5, X and Y have the stated meanings.