method for preparation of derivatives of acids and thienopyridines phenylacetiques phenylacetiques - bromo

摘要

a process for preparation of compounds of formula (i) in which r1 and r2 are identical or different and are each hydrogen or a halogene.according to the invention is characterized in that the reaction is an aldehyde of formula (iv), in which r1 and r2 have the same meaning as in formula (i),with chrr3 and koh in a mixture of inert solvent and water.the products obtained are intermediaries, including the systems composed of formula ii prepared by reaction of an acid ester, bromo, chloro - (2) - tetrahydro - phenylacetique on 4, 5, 6.7 thieno [3,2-c] pyridine derivative in the presence of at least one equivalent of base in a polar solvent