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GAMMA-BUTYROLACTONE DERIVATIVES WITH MYOCARDIUM PROTECTING AND ANTIARRHYTMIC ACTIVITY,PROCESS FOR THEIR PREPARATION AND MEDICINES CONTAINING THEM
GAMMA-BUTYROLACTONE DERIVATIVES WITH MYOCARDIUM PROTECTING AND ANTIARRHYTMIC ACTIVITY,PROCESS FOR THEIR PREPARATION AND MEDICINES CONTAINING THEM
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机译:具有心肌保护作用和抗心律失常作用的γ-丁内酯衍生物,其制备过程和含有它们的药物
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摘要
The present invention relates to the products of general formula: IMAGE (I) in which: R represents a straight or branched alkyl group having from 2 to 5 atoms of carbon, or the group IMAGE represents a morpholino or piperidino group possibly substituted by 1 or 2 methyl groups; n=2 or 3; R1 and R2 considered independently each represent hydrogen or a lower alkyl group (1 to 4 carbon atoms) or R1 and R2 taken together represent a (CH2)m group where m=4 or 5, R3 being equal to H or R1 is H and R2 and R3 considered together represent (CH2)p where p is 3 or 4 the butyrolactone cycle substitutes the pyridyl group in 2', 3' or 4' position, the salts, isomers and mixtures of isomers of said products; and to a process for preparing said products and to the myocardium-protecting drugs containing same.
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