首页> 外国专利> derivatives of cysteine on expectorant action

derivatives of cysteine on expectorant action

机译:半胱氨酸衍生物对祛痰作用的影响

摘要

The present invention covers D or L or DL-cysteine derivatives of the general formula (I) CHEM wherein R represents H or a fatty saturated or unsaturated acid radical, or a radical of an aromatic acid such as benzoic, cynnamic, salycilic, 2-acetoxybenzoic acid or a heterocyclic acid, as well as their salts, in particular the Ca and Mg salts. The invention refers also to a process for preparing said derivatives and to the pharmaceutical preparations containing them as active principle, having a bronchial liquefying and expectorating activity. The derivatives according to the invention may be obtained according to the following reactions: CHEM wherein R represents a hydrocarbon group or a substituted hydrocarbon or or heterocyclic group of the above defined acidic radicals.
机译:本发明涵盖通式(I)的D或L或DL-半胱氨酸衍生物,其中R代表H或脂肪族饱和或不饱和酸基团,或芳族酸的基团,例如苯甲酸,肉桂酸,水杨酸, 2-乙酰氧基苯甲酸或杂环酸,以及它们的盐,特别是Ca和Mg盐。本发明还涉及具有支气管液化和祛痰活性的所述衍生物的制备方法和含有它们作为活性成分的药物制剂。根据本发明的衍生物可以根据以下反应获得:<化学式>其中R代表上述定义的酸性基团的烃基或取代的烃或杂环基。

著录项

  • 公开/公告号IT1228537B

    专利类型

  • 公开/公告日1991-06-20

    原文格式PDF

  • 申请/专利权人 MAGIS FARMACEUTICI SPA;

    申请/专利号IT19870021514

  • 发明设计人 LAURA PURICELLI;

    申请日1987-07-30

  • 分类号A61K;

  • 国家 IT

  • 入库时间 2022-08-22 05:57:05

相似文献

  • 专利
  • 外文文献
  • 中文文献
获取专利

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号