use of 5 - metiltetraidrofolico acid, acid 5 formiltetraidrofolico.and of their salts farmaceuticamente acceptable for the preparation of pharmaceutical compositions in the form of controlled release are likely to be used in the treatment of depressive disorders and compharmaceutical related positions.

摘要

The present invention refers to the use of 5-methyltetrahydrofolic acid, of 5-formyltetrahydrofolic acid and of their pharmaceutically acceptable salts for the preparation of controlled release pharmaceutical compositions suitable for the use in the therapy of depressive disturbances, in particular major depression, dysthymia or depressive neurosis and not otherwise specified depressive disturbances, independently from folate plasmatic levels, and to the pharmaceutical composition thus prepared.