首页>
外国专利>
HYDROGEL DEVICES CONTAINING ACTIVE SUBSTANCES, IN WHICH THE CONCENTRATION PROFILE OF THE ACTIVE SUBSTANCE HAS A SIGMOIDAL CONCENTRATION GRADIENT FOR CONSTANT RELEASE, THEIR PRODUCTION AND USE.
HYDROGEL DEVICES CONTAINING ACTIVE SUBSTANCES, IN WHICH THE CONCENTRATION PROFILE OF THE ACTIVE SUBSTANCE HAS A SIGMOIDAL CONCENTRATION GRADIENT FOR CONSTANT RELEASE, THEIR PRODUCTION AND USE.
展开▼
机译:含有活性物质的氢氧设备,其中活性物质的浓度曲线具有用于持续释放,生产和使用的西格玛浓度梯度。
展开▼
页面导航
摘要
著录项
相似文献
摘要
An active agent containing controlled release diffusion device comprising a swellable hydrogel matrix in the non-swollen state, interpenetrated with an active agent solute having a stable concentration distribution increasing in a gradient normal to the surface of the device and between the surface and the core thereof, said gradient being in the form of a substantially continuous, inflection point containing, sigmoidal curve, such that the device, when placed in an aqueous hydrogel swelling environment, releases said active agent in a controlled continuous manner by diffusion for a predetermined period of time, a method of preparing such a device, and the use thereof to release an active agent into the intended environment of use.
展开▼