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HETEROCYCLIC HYDRAZIDE DERIVATIVES OF MONOCYCLIC BETA-LACTAM ANTIBIOTICS
HETEROCYCLIC HYDRAZIDE DERIVATIVES OF MONOCYCLIC BETA-LACTAM ANTIBIOTICS
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机译:单环β-内酰胺类抗生素的杂环酰肼衍生物
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摘要
GC272 HETEROCYCLIC HYDRAZIDE DERIVATIVES OF MONOCYCLIC BETA-LACTAM ANTIBIOTICS Antibacterial activity has been found in compounds of the formula and pharmaceutically acceptable salts thereof, wherein: A is a bond or alkyl; Q completes a 5- or 6-membered saturated or aromatic heterocyclic ring optionally comprising up to two heteroatoms independently selected from N, NR5, S, O and carbonyl; Y is amino, hydroxy, carboxyl (provided that the heterocyclic ring is not guinoxaline or quinoline), halogen, carboxamide, or nitrile; M? is hydrogen or a cation; and the remaining symbols are as defined in the specification.
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