A clinical applicator (10) for intradermal or subdermal administration of an active substance in a liquid vehicle, such as a vaccine or antigen, has a novel tines structure (26). The tines (26) are provided in the form of an array of eight individual tines (52), each comprising a body member of pyramid shape and having a channel (54) extending from the tip to the base of the body member and having walls at right angles to each other for the length of the channel and to the base. The individual tines (52) are arranged with their apices in a circle and are oriented in two groups of four tines in which the channel of each member forms one corner of a square.
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