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QUANTITATIVE ASSAY OF PROTEIN C USING ACTIVATOR PREPARATION FROM SNAKE VENOM
QUANTITATIVE ASSAY OF PROTEIN C USING ACTIVATOR PREPARATION FROM SNAKE VENOM
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机译:蛇毒中活化剂制备对蛋白质C的定量分析
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摘要
A method and composition for assaying protein C is described. The method comprises reacting a protein C-containing medium with a protein C-activating activator preparation obtained from venom of the snake Agkistrodon contortrix, or venom of another snake species which undergoes an immunological cross-reaction with the venom of Agkistrodon contortrix, to cause maximum activation of protein C and subsequently determining the quantity of activated protein C, said quantity being proportional to the amount of protein C in said medium. Also disclosed is a method and composition for treating thrombotic disorders with the activator preparation and a method of obtaining the activator preparation by culturing of a cloned microorganism.
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