A method and composition for effecting protein accretion in an animal. The composition comprises a hypocaloric dietary component comprising a metabolizable source of nitrogen, carbohydrate, and, optionally, at least one of a triglyceride source, minerals, and vitamins, in conjunction with growth hormone. The method comprises administering an effective amount of the hypocaloric dietary component and growth hormone, orally or parenterally, to effect a positive nitrogen balance under hypocaloric conditions.
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