TRANSDERMAL DELIVERY (+)(2S,3S)-3-ACETOXY-8-CHLORO-5- (2-DIMETHYLAMINOETHYL)-2,3-DIHYDRO-2-(4-METHOXYPHENYL) -1,5-BENZOTHIAZEPIN-4-(5H)-ONE

摘要

A method for treating angina, epilepsy and hypertension by achieving vasodilation, anti-angina or anti-convulsant effect in a patient is described. The method involves transdermally administering to a patient in need of vasodilation or anti-convulsant effect the compound known as (+)(2S,3S)-3-acetoxy-8-chloro-5-(2-dimethylaminoethyl)-2,3-dihydro-2-( 4-methoxyp henyl)-1,5-benzothiazepin-4-(5H)-one in an amount sufficient to achieve desired systemic vasodilation, anti-angina or anti-convulsant levels of the compound.