MAGNETIZABLE COMPOSITE MICROSPHERES BASED ON A CROSSLINKED ORGANOSILICON POLYMER, PROCESS FOR THEIR PREPARATION AND THEIR APPLICATION IN BIOLOGY

摘要

Magnetisable composite microspheres made up of a core consisting of magnetisable fillers distributed uniformly in a lattice of a polysilsesquioxane (SiVi) containing ethylenic unsaturations and a skin made of a crosslinked organosilicon polymer derived from the hydrosilylation of an organohydropolysiloxane (SiH) with the ethylenically unsaturated groups of the polysilsesquioxane SiVi. …??They are obtained by dispersion in a solvent of an aqueous suspension of magnetisable fillers not coated with dispersing agent, dissolving of an alkoxysilane or of an alkoxysiloxane containing ethylenic unsaturations, polycondensation to a polysilsesquioxane SiVi, removal of water, dissolving of the SiH polymer in the organic phase, crosslinking, removal of water, isolation of the microspheres and optionally redispersion in water. …??Use as active support in biology.