PROCESS FOR THE PREPARATION OF L-α-GLYCERYLPHOSPHORYLCHOLINE AND OF L-α-GLYCERYLPHOSPHORYLETHANOLAMINE

摘要

A process is described for the purification of glycerylphosphorylcholine (GPC) and glycerylphosphorylethanolamine (GPE) from crude deacylated mixtures obtained by deacylation of crude or deoleated soy or egg lecithin or of alcoholic extracts thereof comprising: a) the elution on a cationic resin in acid form equilibrated in anhydrous solvent of the crude solutions from the deacylation step; b) washing of the resin with alcohols or water/alcohols; c) obtaining of the pure mixture nGPC+mGPE by washing the resin with water; d) separation of nGPC+mGPE mixture by elution on basic resins to give pure GPC and GPE.