FR-900216 substance obtainable by cultivating ATCC 20577 for use as an active therapeutic substance and pharmaceutical antitumor composition comprising FR-900216 substance

摘要

FR-900216 substance obtainable by cultivating ATCC 20577 in a nutrient medium containing sources of assimilable carbon and nitrogen under aerobic conditions and recovering it from the culture broth and its use as an active therapeutic substance especially for treatment of tumor. The invention covers also a pharmaceutical antitumor composition comprising FR-900216 substance in association with a pharmaceutically acceptable, substantially non-toxic carrier or excipient.