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Complexes of platinum (II) 2,3-dinitrilo-2-butene-2,3-dithiolate, a process for preparing them and pharmaceutical compositions containing them

机译:2,3-二氨基三氯-2-丁烯-2,3-二硫醇铂(II)的配合物,其制备方法以及包含它们的药物组合物

摘要

The invention relates to platinum(II) complexes of 2,3-dimercapto-2-butene-dinitrilate(2-)-S,S' derivatives having the general formula (I): CHEM wherein R is a dialkylsulphide or trialkylphosphine group and each alkyl group may contain one or more hydroxyl groups and has 1 to 2 carbon atoms, as well as to a process for preparing these compounds and to pharmaceutical compositions containing these compounds. These compounds are useful for treating tumor diseases.
机译:本发明涉及具有通式(I)的2,3-二巯基-2-丁烯-二腈(2-)-S,S′衍生物的铂(II)配合物:其中R是二烷基硫化物或三烷基膦基。以及每个烷基可含有一个或多个羟基并具有1-2个碳原子,以及制备这些化合物的方法和含有这些化合物的药物组合物。这些化合物可用于治疗肿瘤疾病。

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