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Assaying the duchenne muscular dystrophy protein deletion or defect
Assaying the duchenne muscular dystrophy protein deletion or defect
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机译:检测杜氏肌营养不良蛋白的缺失或缺陷
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摘要
This invention provides a method for assaying for the protein deletion or defect associated with the human DMD gene, which comprises preparing a peptide which contains at least part of an amino acid sequence encoded by a Duchenne muscular dystrophy gene or a derivative thereof, administering said peptide or derivative thereof to a mammal to form antiserum, then combining said antiserum, or an antibody fraction separated from said antiserum, with a substance to be tested and assaying for any antigen-antibody complex formed.;It also provides methods for preparing the antiserum by use of part of the amino acid sequence encoded by the human Duchenne muscular dystrophy gene. The invention also provides kits and reagents for such assays.
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