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11-norsteroid having an amide or carbamate functional group-containing hydrocarbon chain at 11-beta position, its preparation method and intermediates, drug application and pharmaceutical composition containing them
11-norsteroid having an amide or carbamate functional group-containing hydrocarbon chain at 11-beta position, its preparation method and intermediates, drug application and pharmaceutical composition containing them
The invention relates to the products of formula i: & br / (see appended drawing in bopi) & br / in which: - rings a and b represent, in particular, the group: & br / (see appended drawing in bopi) & br / - r1 7: in particular oh or acyloxy, r ′ 1 - 7: in h, alkyl, alkenyl or alkynyl, optionally substituted, - x: methylene, arylene, ch2 o or aryleneoxy, - y: simple link, or aliphatic chain c1 - 1 8 may be interrupted or terminated by an arylene, - z: single bond or ch2 o - ra and r a = h, alkyl, c1 - 8 which is optionally substituted or form a heterocycle with the nitrogen atom, 1 / p & & p & their preparation process and intermediates for their application as medicinal products and the pharmaceutical compositions containing them.
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