STRAIN OF HYBRIDOUS CULTURED MAMMALIAN CELLS, MUS MUSCULUS L - A PRODUCER OF MONOCLONAL ANTIBODIES FOR M-PROTEIN OF INFLUENZA VIRUS TYPE A

摘要

the invention u043eu0442u043du043eu0441u0438u0442u0441u00a0 to u0433u0438u0431u0440u0438u0434u043eu043cu043du043eu0439 technology and can be used u0434u043bu00a0 development of diagnostic test systems.the purpose of u0438u0437u043eu0431u0440u0435u0442u0435u043du0438u00a0 is a strain of hybrid cells, producing u0442u0438u043fu043eu0441u043fu0435u0446u0438u0444u0438u0447u0435u0441u043au0438u0435 monoclonal antibodies to u0430u043du0442u0438u0433u0435u043du043du043eu0439 u0434u0435u0442u0435u0440u043cu0438u043du0430u043du0442u0435 m protein influenza virus t ipu and the common u0434u043bu00a0 different u043fu043eu0434u0442u0438u043fu043eu0432 strain produced in the cells of spleen of mice BALB hybridization / cimmunized subjects, protein influenza virus t pa and (leningrad) 385 / 80 Ri (H3N2) were u044du043bu0435u043au0433u0440u043eu0444u043eu0440u0435u0442u0438u0447u0435u0441u043au0438 by detergent u0434u0435u0437u0438u043du0442u0435u0433u0440u043eu043du0430 - 0cells u043cu0438u0435u043bu043eu043cu043du043eu0439 line 363 - u0430u04348 653 u0441u0435u043au0440u0435u0442u0438u0440u0443u0435u043cu043eu0435 u0433u0438u0434u0440u0438u0434u043eu043cu043eu0439 u043cu043eu043du043eu043au043bu043eu043du0430u043bu044c ous u0441u0432u00a0u0437u044bu0432u0430u0435u0442u0441u00a0 antibody to m protein influenza virus type a different u043fu043eu0434u0442u0438u043fu043eu0432 strain culture u0442u0438u0432u0438u0440u0443u0435u0442u0441u00a0 standard u0443u0435u043bu043e u0432u0438u00a0u0445 u0434u043bu00a0 u0432u044bu0440u0430u0449u0438u0432u0430u043du0438u00a0 hybrid and easy u043fu0435u0440u0435u0432u043eu0434u0438u0442u0441u00a0 in u0430u0441u0446u0438u0442u0438u0447u0435u0441u043au0443u044e form productivity of strain 20 micrograms / il-2 in the culture fluid and general 5.8 mg / ml in u0430u0441u0446u0438u0442u0438u0447u0435u0441u043au043eu0439 fluid.the strain is deposited with the no. u0432u0441u043au043a (p) 354D with with